Fetal Valproate Syndrome with Limb Defects: An Indian Case Report
نویسندگان
چکیده
منابع مشابه
Fetal Valproate Syndrome with Limb Defects: An Indian Case Report
Epilepsy is a common disorder and exposure to antiepileptic drugs during pregnancy increases the risk of teratogenicity. Older AEDs such as valproate and phenobarbital are associated with a higher risk of major malformations in the fetus than newer AEDs like lamotrigine and levetiracetam. Exposure to valproic acid during first trimester can result in fetal valproate syndrome (FVS), comprising t...
متن کاملPrenatal sonographic diagnosis of fetal valproate syndrome: a case report
BACKGROUND Prenatal exposure of mother to valproate (VPA) causes teratogenic effects in the fetus, namely fetal valproate syndrome (FVS). We report a case of fetal valproate syndrome rarely diagnosed by prenatal sonographic examination. CASE PRESENTATION Our patient was a female infant who was born to a 27-year-old nulliparous Japanese woman with epilepsy. The mother was diagnosed with infant...
متن کاملFetal valproate syndrome.
There is an increased incidence of major and minor congenital abnormalities in infants born to epileptic mothers (6 to 7% compared with 2 to 3% in the general population).' Factors which may contribute to this include the occurrence of seizures leading to periods of hypoxia during pregnancy, an inherited predisposition to malformations owing to intrinsic maternal factors, and the teratogenic ef...
متن کاملFetal valproate syndrome in a 14-month-old child: A case report
Anti-epileptic drugs administered during pregnancy can cause structural defects in the growing fetus and result in adverse neurodevelopmental outcome later in life. Fetal valproate syndrome (FVS) results from teratogenic effects of valproic acid exposure in the prenatal period. It is characterised by a distinctive dysmorphic facies and a cluster of minor and major anomalies, as well as developm...
متن کاملStiff limb syndrome: a case report
INTRODUCTION Stiff limb syndrome is a clinical feature of the stiff person syndrome, which is a rare and disabling neurologic disorder characterized by muscle rigidity and episodic spasms that involve axial and limb musculature. It is an autoimmune disorder resulting in a malfunction of aminobutyric acid mediated inhibitory networks in the central nervous system. We describe a patient diagnosed...
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ژورنال
عنوان ژورنال: Case Reports in Pediatrics
سال: 2016
ISSN: 2090-6803,2090-6811
DOI: 10.1155/2016/3495910